The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Overview

This section was extensively revised.

Pathogenesis of Fatigue

This section was extensively revised.

Contributing Factors

Added hormonal excess, physical deconditioning, proinflammatory cytokines, nutritional deficiencies, and dehydryation as factors correlated with fatigue in cancer patients.

Added text on proinflammatory cytokines (cited Collado-Hidalgo et al. and Wood et al. as references 9 and 10, respectively).

Intervention

Added text on buproprion (cited Moss et al. as reference 9).

Added text on the effects of exercise on prostate cancer patients (cited Monga et al. as reference 24). Also added text on the effects of physical activity on breast cancer survivors (cited Alfano et al. as reference 31).

Added Dy et al. as reference 36.

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